Identification of signatures associated with microsatellite instability and immune characteristics to predict the prognostic risk of colon cancer

Abstract

Microsatellite instability (MSI) significantly impacts treatment response and outcomes in colon cancer; however, its underlying molecular mechanisms remain unclear. This study aimed to identify prognostic biomarkers by comparing MSI and microsatellite stability (MSS).

Keywords

• colon cancer
• microsatellite instability
• immune microenvironment
• prognostic model
• weighted gene co-expression network analysis