Acta Crystallographica Section E (Apr 2009)

4-(3-Methoxyphenoxy)butyric acid

  • Julia Heilmann-Brohl,
  • Gérard Jaouen,
  • Michael Bolte

DOI
https://doi.org/10.1107/s1600536809008186
Journal volume & issue
Vol. 65, no. 4
pp. o778 – o778

Abstract

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In the title compound, C11H14O4, an intermediate for the synthesis of a new kind of estrogen receptor modulator, all non-H atoms lie on a common plane (r.m.s. deviation = 0.0472 Å). All C—C bonds in the side chain are in a trans conformation, and the hydroxyl group is also trans to the methylene chain. In the crystal structure, molecules form centrosymmetric dimers showing a head-to-head arrangement which is stabilized by O—H...O hydrogen bonds. A weak C—H...O contact is also present.