Research progress on the correlation between blood⁃brain barrier and cerebral small vessel disease

KONG Qian⁃qian; HUANG Hao; LUO Xiang

doi:10.3969/j.issn.1672⁃6731.2023.11.004

Chinese Journal of Contemporary Neurology and Neurosurgery (Nov 2023)

Research progress on the correlation between blood⁃brain barrier and cerebral small vessel disease

KONG Qian⁃qian,
HUANG Hao,
LUO Xiang

Affiliations

KONG Qian⁃qian: Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China
HUANG Hao: Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China
LUO Xiang: Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China

DOI: https://doi.org/10.3969/j.issn.1672⁃6731.2023.11.004
Journal volume & issue: Vol. 23, no. 11
pp. 972 – 977

Abstract

Read online

Cerebral small vessel disease (CSVD) is a leading cause of stoke and vascular dementia, and its pathogenesis remains unclear. Research on brain histopathology has identified that the blood⁃brain barrier plays a crucial role in the pathogenesis and progression of CSVD. This article reviews the research progress on the correlation between blood ⁃ brain barrier and CSVD from imaging biomarkers, blood biomarkers and pathophysiology, to provide ideas for better diagnosis and treatment of CSVD.

Published in Chinese Journal of Contemporary Neurology and Neurosurgery

ISSN: 1672-6731 (Print)
Publisher: Tianjin Huanhu Hospital
Country of publisher: China
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry: Neurology. Diseases of the nervous system
Website: http://www.cjcnn.org/index.php/cjcnn

About the journal

Abstract

Keywords