Combination of metabolome and proteome analyses provides insights into the mechanism underlying growth differences in Acipenser dabryanus

Xiaoyun Wu; Jiansheng Lai; Yeyu Chen; Ya Liu; Mingjiang Song; Feiyang Li; Pengcheng Li; Qingzhi Li; Quan Gong

iScience (Aug 2023)

Combination of metabolome and proteome analyses provides insights into the mechanism underlying growth differences in Acipenser dabryanus

Xiaoyun Wu,
Jiansheng Lai,
Yeyu Chen,
Ya Liu,
Mingjiang Song,
Feiyang Li,
Pengcheng Li,
Qingzhi Li,
Quan Gong

Affiliations

Xiaoyun Wu: The Fishery Institute of the Sichuan Academy of Agricultural Sciences, Chengdu 611730, China; Fish Resources and Environment in the Upper Reaches of the Yangtze River Observation and Research Station of Sichuan Province, Chengdu 611730, China
Jiansheng Lai: The Fishery Institute of the Sichuan Academy of Agricultural Sciences, Chengdu 611730, China; Fish Resources and Environment in the Upper Reaches of the Yangtze River Observation and Research Station of Sichuan Province, Chengdu 611730, China
Yeyu Chen: The Fishery Institute of the Sichuan Academy of Agricultural Sciences, Chengdu 611730, China; Fish Resources and Environment in the Upper Reaches of the Yangtze River Observation and Research Station of Sichuan Province, Chengdu 611730, China
Ya Liu: The Fishery Institute of the Sichuan Academy of Agricultural Sciences, Chengdu 611730, China; Fish Resources and Environment in the Upper Reaches of the Yangtze River Observation and Research Station of Sichuan Province, Chengdu 611730, China
Mingjiang Song: The Fishery Institute of the Sichuan Academy of Agricultural Sciences, Chengdu 611730, China; Fish Resources and Environment in the Upper Reaches of the Yangtze River Observation and Research Station of Sichuan Province, Chengdu 611730, China
Feiyang Li: The Fishery Institute of the Sichuan Academy of Agricultural Sciences, Chengdu 611730, China; Fish Resources and Environment in the Upper Reaches of the Yangtze River Observation and Research Station of Sichuan Province, Chengdu 611730, China
Pengcheng Li: The Fishery Institute of the Sichuan Academy of Agricultural Sciences, Chengdu 611730, China; Fish Resources and Environment in the Upper Reaches of the Yangtze River Observation and Research Station of Sichuan Province, Chengdu 611730, China
Qingzhi Li: The Fishery Institute of the Sichuan Academy of Agricultural Sciences, Chengdu 611730, China; Fish Resources and Environment in the Upper Reaches of the Yangtze River Observation and Research Station of Sichuan Province, Chengdu 611730, China
Quan Gong: The Fishery Institute of the Sichuan Academy of Agricultural Sciences, Chengdu 611730, China; Fish Resources and Environment in the Upper Reaches of the Yangtze River Observation and Research Station of Sichuan Province, Chengdu 611730, China; Corresponding author

Journal volume & issue: Vol. 26, no. 8
p. 107413

Abstract

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Summary: To analyze the differences between different-sized Acipenser dabryanus, we randomly selected 600 3-month-old A. dabryanus juveniles. Four months later, the blood and white muscle of these fish were analyzed. The results showed no significant difference in the length-weight relationship (LWR) b value between the large and small A. dabryanus. The levels of serum growth hormone (gh) and insulin-like growth factor 1 (igf1) in the large A. dabryanus were significantly lower than those in the small, whereas the activity levels of Total superoxide dismutase (T-sod) and catalase (cat) were opposite to the results of gh and igf1. A total of 212 and 245 metabolites showed significant changes in the positive and negative polarity mode, respectively. Among 3,308 proteins identified, 69 proteins showed upregulated expression, and 185 proteins showed downregulated expression. These results indicated that the growth advantage of A. dabryanus was closely related to glycolysis, protein synthesis, and antioxidant function.

Published in iScience

ISSN: 2589-0042 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Science
Website: http://www.cell.com/iscience/home

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