Radiology Case Reports (Mar 2023)

A rare case of cytomegalovirus hepatitis mimicking malignancy in an immunocompetent adult

  • Nimisha Manek, MD,
  • Samuel Conyngham, MD,
  • Melinda Tram Thi Ngoc Nguyen, MBBS,
  • Thao Lam, MD,
  • Chow P'Ng, MD,
  • Anthony Peduto, MD

Journal volume & issue
Vol. 18, no. 3
pp. 1164 – 1168

Abstract

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Cytomegalovirus (CMV) is a highly prevalent pathogen that remains dormant in majority of the cases. Severe CMV infection is generally limited to immunocompromised hosts. While occasional cases of CMV hepatitis are observed in healthy immunocompetent hosts, it is very rare to find this associated with focal liver lesions mimicking malignancy. Cases of non-immunosuppressed CMV reactivation, CMV-associated liver lesions, and CMV-associated portal vein thrombosis have all been reported individually, we present a single case of CMV with all of these rare manifestations.

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