Pharmacological Research - Modern Chinese Medicine (Jun 2024)
Biological potential of aromadendrin against human disorders: Recent development in pharmacological activities and analytical aspects
Abstract
Introduction: Medicinal plants have played an essential role in the treatment of human diseases and their associated secondary complications since early childhood in the medical systems of China, India, Korea, and Japan. Aromadendrin is a phytochemical member of the flavonoid class found in many medicinal plants such as Persica vulgaris, Chionanthus retusus, Populus davidiana, Olea europaea, Spatholobus suberectus, Akschindlium godefroyanum, Chionanthus retusu, Cudrania tricuspidata, Populus davidiana, Hemiptelea davidii and Gelditsia sinensis. The purpose of this article is to summarize scientific information on the medicinal efficacy, pharmacological activity, and analytical aspects of aromadendrin in medicine. Methods: This article discusses the biological significance and therapeutic effects of aromadendrin along with its analytical aspects to know the therapeutic potential of aromadendrin in medicine. All scientific information about aromadendrin was collected from Google, PubMed, Scopus, and Science Direct. Additionally, aromadendrin belongs to the flavonoid class, so to know its health benefits, the biological importance of flavonoids will also be discussed in this article. Additionally, the analytical aspects of aromadendrin are also discussed in this article. Results: This article discusses the biological significance and therapeutic efficacy of aromadendrin in the treatment of human diseases. This study reveals aromadendrin immunosuppressive, antiproliferative, anti-inflammatory, gastroprotective, antibacterial, trypanocidal, anticandida, antioxidant and cytotoxic potential in medicine. In addition, aromadendrin also has significant effects on cardiac hypertrophy, glucose absorption, non-small cell lung cancer, liver damage, acute pancreatitis, enzymes, and multidrug resistance. However, analytical parameters for aromadendrin separation, isolation, and identification are also discussed in this article. Discussion and conclusion: Present work described the different pharmacological activities of aromadendrin with their molecular mechanism. The present study provides new insights into the biological applications of aromadendrin and will help explore its therapeutic potential for many types of human diseases. This study will help understand the biological potential and benefits of aromadendrin in medicine.