Use of statins in primary prevention of coronary artery disease: new data on risk-benefit balance

Abstract

The article reviews current approaches to primary prevention of cardiovascular events and risk-benefit balance in the use of statin therapy in healthy people at risk of cardiovascular disease; the results of large clinical trials evaluating the efficacy of statins used for primary prevention; safety of statins, particularly, a higher risk of developing diabetes; different approaches to the selection of necessary and sufficient doses of statins in primary prevention.

Keywords

• первичная профилактика
• сердечнососудистые заболевания
• статины
• primary prevention
• cardiovascular events
• statins