A novel overlap syndrome: Rheumatoid arthritis, Sjogren's syndrome, antiphospholipid syndrome, and dermatomyositis

Abstract

Key Clinical Message This is an extremely rare case that has not been presented or discussed in the literature to the best of our knowledge. The overlap of connective tissue disease is a challenge for physicians and patients, and it needs special care and regular clinical and laboratory follow‐up. Abstract This report describes a rare case of overlapping connective tissue diseases in a 42‐year‐old female with rheumatoid arthritis, Sjogren's syndrome, antiphospholipid syndrome, and dermatomyositis. The patient presented with a hyperpigmented erythematous rash, muscle weakness, and pain, highlighting the challenges of diagnosis and treatment that require regular clinical and laboratory follow‐up.

Keywords

• antiphospholipid syndrome
• dermatomyositis
• overlap syndrome
• rheumatoid arthritis
• Sjogren's syndrome