Confinement of Therapeutic Enzymes in Selectively Permeable Polymer Vesicles by Polymerization-Induced Self-Assembly (PISA) Reduces Antibody Binding and Proteolytic Susceptibility

• Lewis D. Blackman,
• Spyridon Varlas,
• Maria C. Arno,
• Zachary H. Houston,
• Nicholas L. Fletcher,
• Kristofer J. Thurecht,
• Muhammad Hasan,
• Matthew I. Gibson,
• Rachel K. O’Reilly

Affiliations

Lewis D. Blackman

Department of Chemistry, University of Warwick, Coventry, United Kingdom

Spyridon Varlas

Department of Chemistry, University of Warwick, Coventry, United Kingdom

Maria C. Arno

Department of Chemistry, University of Warwick, Coventry, United Kingdom

Zachary H. Houston

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St. Lucia, Queensland, Australia

Nicholas L. Fletcher

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St. Lucia, Queensland, Australia

Kristofer J. Thurecht

Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St. Lucia, Queensland, Australia

Muhammad Hasan

Department of Chemistry, University of Warwick, Coventry, United Kingdom

Matthew I. Gibson

Department of Chemistry, University of Warwick, Coventry, United Kingdom

Rachel K. O’Reilly

Department of Chemistry, University of Warwick, Coventry, United Kingdom