Primary gastric squamous cell carcinoma: A diagnostic dilemma

Abstract

Primary gastric squamous cell carcinoma (SCC) is an extremely rare entity with very few cases reported worldwide. We present a case of a large locally advanced gastric mass with liver metastasis, with no involvement of the gastric mucosa. Clinical presentation, serum markers, imaging, endoscopy, and histopathology, created a dilemma in its diagnosis. However, immunohistochemistry helped in the diagnosis. This case serves as a reminder to consider primary gastric SCC as a differential while evaluating a gastric mass.

Keywords

• primary gastric squamous cell carcinoma
• metastatic carcinoma
• poorly differentiated carcinoma of the stomach
• gastric cancer
• pgscc