NK cells enhance CAR-T cell antitumor efficacy by enhancing immune/tumor cells cluster formation and improving CAR-T cell fitness

• Amer Najjar,
• Manel Juan,
• Lorena Pérez-Amill,
• Alvaro Urbano-Ispizua,
• Beatriz Martín-Antonio,
• Mireia Bachiller,
• Anthony Matthew Battram,
• Sebastian Ciro Carné,
• Els Verhoeyen

Affiliations

Amer Najjar

Department of Pediatrics-Research, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Manel Juan

Department of Immunology, Hospital Clinic de Barcelona (HCB), Platforms of Immunoterapy IDIBAPS HSJD-HCB and BST-HCB, Barcelona, Spain

Lorena Pérez-Amill

Department of Hematology, Hospital Clinic, IDIBAPS, Barcelona, Spain

Alvaro Urbano-Ispizua

Department of Hematology. University of Barcelona, IDIBAPS, Barcelona, Spain

Beatriz Martín-Antonio

Department of Experimental Hematology, Instituto de Investigación Sanitaria-Fundación Jiménez Diaz, Madrid, Spain

Mireia Bachiller

Department of Hematology, Hospital Clinic, IDIBAPS, Barcelona, Spain

Anthony Matthew Battram

Department of Hematology, Hospital Clinic, IDIBAPS, Barcelona, Spain

Sebastian Ciro Carné

Department of Hematology, Hospital Clinic, IDIBAPS, Barcelona, Spain

Els Verhoeyen

CIRI, Université de Lyon, INSERM U1111, ENS de Lyon, Université Lyon 1, Lyon, France