Low molecular weight thymic factor inhibits histamine release from basophils

S. I. Yalkut; E. V. Gulling; T. Yu. Gots; S. A. Kotova; O. B. Belova; V. Ch. Premyslov

doi:10.1155/S0962935193000638

Mediators of Inflammation (Jan 1993)

Low molecular weight thymic factor inhibits histamine release from basophils

S. I. Yalkut,
E. V. Gulling,
T. Yu. Gots,
S. A. Kotova,
O. B. Belova,
V. Ch. Premyslov

Affiliations

S. I. Yalkut: R.E. Kavetsky Institute of Experimental Pathology, Onkology and Radiobiology, Acad. Sci. of Ukraine, ul. Vasilkovscaja 45, Kiev 252650, Ukraine
E. V. Gulling: Kiev Advanced Training Institute for Physicians, Clinical Immunology and Allergology Department, Dorogozshitskaya 9, Kiev 252112, Ukraine
T. Yu. Gots: Kiev Advanced Training Institute for Physicians, Clinical Immunology and Allergology Department, Dorogozshitskaya 9, Kiev 252112, Ukraine
S. A. Kotova: R.E. Kavetsky Institute of Experimental Pathology, Onkology and Radiobiology, Acad. Sci. of Ukraine, ul. Vasilkovscaja 45, Kiev 252650, Ukraine
O. B. Belova: R.E. Kavetsky Institute of Experimental Pathology, Onkology and Radiobiology, Acad. Sci. of Ukraine, ul. Vasilkovscaja 45, Kiev 252650, Ukraine
V. Ch. Premyslov: R.E. Kavetsky Institute of Experimental Pathology, Onkology and Radiobiology, Acad. Sci. of Ukraine, ul. Vasilkovscaja 45, Kiev 252650, Ukraine

DOI: https://doi.org/10.1155/S0962935193000638
Journal volume & issue: Vol. 2, no. 6
pp. 443 – 446

Abstract

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Low molecular weight thymic factor stimulates the suppressor function of T-lymphocytes, increases cAMP content (but not cGMP) in lymphocytes and inhibits histamine release from sensitized basophils. The mechanisms of LTF action are discussed.

Published in Mediators of Inflammation

ISSN: 0962-9351 (Print); 1466-1861 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Pathology
Website: https://onlinelibrary.wiley.com/journal/4792

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