Journal of Education, Health and Sport (Jun 2017)

Extracellular matrix change in patients with various forms of atrial fibrillation

  • A. V. Goryachiy,
  • A. I. Gozhenko,
  • E. M. Levchenko,
  • V. V. Goriachyi,
  • M. A. Kuznetsova,
  • M. I. Arapu

DOI
https://doi.org/10.5281/zenodo.1472947
Journal volume & issue
Vol. 7, no. 6
pp. 1223 – 1235

Abstract

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Purpose: We studied the change in serum collagen markers in patients with various forms of atrial fibrillation (AF) Methods: Collagen type C-terminal propeptide (CTPK-I), C-terminal telopeptide of type I collagen (CTTK-I), matrix metalloproteinase I, and tissue inhibitors of matrix metalloproteinase I were used as markers for collagen synthesis. The study group comprised - 70 people, control - 20. Results: The level of CTCP-I and CTTP-I in patients with AF was significantly higher in comparison with the control group (91 +27 ng / ml, 67 + 11 ng / ml, p

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