Focus on HPV Infection and the Molecular Mechanisms of Oral Carcinogenesis
Luigi Santacroce,
Michele Di Cosola,
Lucrezia Bottalico,
Skender Topi,
Ioannis Alexandros Charitos,
Andrea Ballini,
Francesco Inchingolo,
Angela Pia Cazzolla,
Gianna Dipalma
Affiliations
Luigi Santacroce
Interdisciplinary Department of Medicine, Microbiology and Virology Unit, School of Medicine, University of Bari “A. Moro”, 70124 Bari, Italy
Michele Di Cosola
Department of Clinical and Experimental Medicine, Università degli Studi di Foggia, 71122 Foggia, Italy
Lucrezia Bottalico
Interdepartmental Research Center for Pre-Latin, Latin and Oriental Rights and Culture Studies (CEDICLO), University of Bari “A. Moro”, 70121 Bari, Italy
Skender Topi
Interdepartmental Research Center for Pre-Latin, Latin and Oriental Rights and Culture Studies (CEDICLO), University of Bari “A. Moro”, 70121 Bari, Italy
Ioannis Alexandros Charitos
Interdepartmental Research Center for Pre-Latin, Latin and Oriental Rights and Culture Studies (CEDICLO), University of Bari “A. Moro”, 70121 Bari, Italy
Andrea Ballini
Department of Biosciences, Biotechnologies and Biopharmaceutics, Campus Universitario “G. Quagliarello”, University of Bari “A. Moro”, 70125 Bari, Italy
Francesco Inchingolo
Interdisciplinary Department of Medicine, University of Bari “A. Moro”, 70124 Bari, Italy
Angela Pia Cazzolla
Department of Clinical and Experimental Medicine, Università degli Studi di Foggia, 71122 Foggia, Italy
Gianna Dipalma
Interdisciplinary Department of Medicine, University of Bari “A. Moro”, 70124 Bari, Italy
This study is focused on the epidemiological characteristics and biomolecular mechanisms that lead to the development of precancerous and cancerous conditions of oral lesions related to Human Papilloma Virus (HPV) infections. Current evidence from the literature demonstrates the role of HPV in potentially malignant oral disorders. Therefore, the underlying biomolecular processes can give arise, or contribute to, benign lesions as well as to oral carcinogenesis.
