Nature Communications (Nov 2022)

Generalizable spelling using a speech neuroprosthesis in an individual with severe limb and vocal paralysis

  • Sean L. Metzger,
  • Jessie R. Liu,
  • David A. Moses,
  • Maximilian E. Dougherty,
  • Margaret P. Seaton,
  • Kaylo T. Littlejohn,
  • Josh Chartier,
  • Gopala K. Anumanchipalli,
  • Adelyn Tu-Chan,
  • Karunesh Ganguly,
  • Edward F. Chang

DOI
https://doi.org/10.1038/s41467-022-33611-3
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 15

Abstract

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Previous work has described a neuroprosthesis to directly decode full words in real time during attempts to speak. Here the authors demonstrate that a patient with anarthria can control this neuroprosthesis to spell out intended messages in real time using attempts to silently speak.