P-70 SEROPREVALENCE OF HEPATITIS C VIRUS IN DONORS OF THE BLOOD BANK OF THE GENERAL HOSPITAL OF MEXICO 'DR. EDUARDO LICEAGA' A FOUR-YEAR EVALUATION

Abstract

Introduction: Since the molecular identification of the hepatitis C virus (HCV) in 1989 and the development of antibodies as an initial part of the diagnosis of this infection, blood banks have taken an important step to exclude potential donors with this infection, the World Health Organization established as a mandatory measure, the screening of all blood donated for transfusion for communicable infections such as HCV, HBV, HIV and HTLV as a mandatory measure. HCV affects between 130 and 150 million people worldwide, with a global prevalence of around 2.2%, and is the cause of 27% of cirrhosis cases and 25% of primary hepatocellular carcinoma cases in the world. In developed countries. Objetive: To evaluate the seroprevalence of HCV and risk factors in potential blood donors in a tertiary hospital for 4 years. Methods: Retrospective, observational, cross-sectional, descriptive study carried out in blood donors at the Hospital General de México ''Dr. Eduardo Liceaga.'' From January 1, 2016, to December 31, 2019. Donor files were reviewed, and those with HCV positivity were analyzed. The SPSS v 22 program was used for statistical analysis. Results: 92,214 donors were included. Of these, 1,265 patients (1.37%), 449 women (35%) and 816 men (64.5%) were positive. Risk factors found in the positive group: alcoholism 153 (12.09%), dental surgery 128 (10.11%). tattoos (6.87%), piercings (7.19%), acupuncture (3.08%) and risky sexual partners (0.23%). Conclusion: The prevalence of 1.37% is similar to that reported in the literature; the predominance is slightly in the group of men, which contrasts with the past years that due to obstetric events, women were the most prevalent, perhaps it is related to tattoos, piercings, and use of intravenous or intranasal drugs. Although all the donors were approved in the official questionnaire, the positivity may be related to factors not declared by the patients themselves.