Exercise training modulates the gut microbiota profile and impairs inflammatory signaling pathways in obese children

Abstract

Childhood obesity: working out for a healthier microbiome Physical fitness regimens could stimulate shifts in gut microbiome composition and metabolism that counteract health risks associated with childhood obesity. This condition can increase the risk of metabolic and cardiovascular disease later in life. Several studies have indicated that disturbances in the microbial populations in the digestive tract may contribute to these diseases. Researchers led by Sonia Sánchez-Campos of the Institute of Biomedicine, León,Spain, recently assessed the impact of exercise and endurance training on microbiome composition in obese children. They determined that these regimens can produce measurable shifts in the gut microbe population, yielding bacterial communities that are more similar to those seen in non-obese children. These shifts were accompanied by alterations in metabolic activity that may help mitigate inflammatory signaling and other processes that fuel obesity-related disease.