Exploring terahertz spectral characteristics of L-sorbose and D-melibiose in solid and liquid states
Boyan Zhang,
Yuhan Zhao,
Jingyi Shu,
Bingxin Yan,
Bo Peng,
Siyu Qian,
Bo Su,
Cunlin Zhang
Affiliations
Boyan Zhang
Key Laboratory of Terahertz Optoelectronics, Ministry of Education, Beijing 100048, China; Beijing Key Laboratory for Terahertz Spectroscopy and Imaging, Beijing 100048, China; Beijing Advanced Innovation Centre for Imaging Theory and Technology, Beijing 100048, China; Department of Physics, Capital Normal University, Beijing 100048, China
Yuhan Zhao
Key Laboratory of Terahertz Optoelectronics, Ministry of Education, Beijing 100048, China; Beijing Key Laboratory for Terahertz Spectroscopy and Imaging, Beijing 100048, China; Beijing Advanced Innovation Centre for Imaging Theory and Technology, Beijing 100048, China; Department of Physics, Capital Normal University, Beijing 100048, China
Jingyi Shu
Key Laboratory of Terahertz Optoelectronics, Ministry of Education, Beijing 100048, China; Beijing Key Laboratory for Terahertz Spectroscopy and Imaging, Beijing 100048, China; Beijing Advanced Innovation Centre for Imaging Theory and Technology, Beijing 100048, China; Department of Physics, Capital Normal University, Beijing 100048, China
Bingxin Yan
Key Laboratory of Terahertz Optoelectronics, Ministry of Education, Beijing 100048, China; Beijing Key Laboratory for Terahertz Spectroscopy and Imaging, Beijing 100048, China; Beijing Advanced Innovation Centre for Imaging Theory and Technology, Beijing 100048, China; Department of Physics, Capital Normal University, Beijing 100048, China
Bo Peng
Key Laboratory of Terahertz Optoelectronics, Ministry of Education, Beijing 100048, China; Beijing Key Laboratory for Terahertz Spectroscopy and Imaging, Beijing 100048, China; Beijing Advanced Innovation Centre for Imaging Theory and Technology, Beijing 100048, China; Department of Physics, Capital Normal University, Beijing 100048, China
Siyu Qian
Key Laboratory of Terahertz Optoelectronics, Ministry of Education, Beijing 100048, China; Beijing Key Laboratory for Terahertz Spectroscopy and Imaging, Beijing 100048, China; Beijing Advanced Innovation Centre for Imaging Theory and Technology, Beijing 100048, China; Department of Physics, Capital Normal University, Beijing 100048, China
Bo Su
Key Laboratory of Terahertz Optoelectronics, Ministry of Education, Beijing 100048, China; Beijing Key Laboratory for Terahertz Spectroscopy and Imaging, Beijing 100048, China; Beijing Advanced Innovation Centre for Imaging Theory and Technology, Beijing 100048, China; Department of Physics, Capital Normal University, Beijing 100048, China; Corresponding author
Cunlin Zhang
Key Laboratory of Terahertz Optoelectronics, Ministry of Education, Beijing 100048, China; Beijing Key Laboratory for Terahertz Spectroscopy and Imaging, Beijing 100048, China; Beijing Advanced Innovation Centre for Imaging Theory and Technology, Beijing 100048, China; Department of Physics, Capital Normal University, Beijing 100048, China
Summary: Saccharides are essential organic compounds that perform critical functions in sustaining life processes. As biomolecules, their vibrational frequencies predominantly fall in the terahertz (THz) range, making them amenable to analysis using THz techniques. In this study, L-sorbose and D-melibiose were measured using a THz time-domain spectroscopy system covering a frequency range of 0.1–2.0 THz, and their crystal structures were simulated using density functional theory. The experimental results demonstrated significant agreement with the simulation findings. In addition, the spectral properties of the two saccharides in solution were determined using microfluidic chip technology, thereby facilitating a comparison between the solid and aqueous states. The results demonstrate that the intramolecular and intermolecular interactions of the saccharides were weakened by the presence of water molecules, and the THz absorption spectrum of the same substance solution was found to be correlated with its concentration and temperature.
