Advances in Laboratory Medicine (Apr 2024)

Interference of metamizole in the measurement of serum creatinine concentration

  • Castro-Castro María-José,
  • Cachón-Suárez Isabel,
  • Maestre-Fernández Andrea,
  • Navarro-Badal Rosa

DOI
https://doi.org/10.1515/almed-2023-0163
Journal volume & issue
Vol. 5, no. 3
pp. 291 – 295

Abstract

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There is little literature on the interference of metamizole in measurement creatinine concentration by the enzymatic method. Some studies have postulated that the dipyrone molecule is responsible for interfering in the last reaction of the enzymatic method sequence, due to its similarity with the 4-aminophenazone molecule. The aim of this study is to examine the interference of the presence of metamizole in the measurement of serum creatinine concentration by the enzymatic method.

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