Synthesis, characterization, and antimicrobial activites of some dithiophosphate silane complexes

Abstract

The compounds MeCl2Si[S2P(OR)2], MeClSi[S2POGO]2, and MeSi[S2P(OR)2]3 (where R=Et, n-Pr, i-Pr, i-Bu, and Ph; G=-CH2CMe2CH2-, -CH2CEt2CH2-, and -CMe2CMe2-) have been prepared by reacting the sodium salt of the appropriate dithiophosphoric acid or the acid itself with MeSiCl3 in 1:1, 1:2, and 1:3 molar ratios, in benzene, at reflux. These compounds are yellow oily liquids and soluble in common organic solvents. The molecular weight determination corresponds to monomers. The compounds have been characterized by elemental analysis and by 1H, 13C, 29Si, and 31P NMR spectroscopies. The ligands coordinate in a monodentate mode to the silicon atoms which in turn show a tetrahedral environment. Screening these complexes for their antibacterial activities gave positive results.

Keywords

• dialkyl and alkylene dithiophosphates
• dialkyl and alkylene dithiophosphates of methylsilane
• methylsilane dithiophosphates