Case Reports in Clinical Practice (Nov 2023)

Infectious Mononucleosis Mimicking Acute Lymphoblastic Leukemia (ALL): ACase Report

  • Maassoumeh Akhlaghi,
  • Kiarash Kazemi,
  • Soheila Sobhani

DOI
https://doi.org/10.18502/crcp.v8i2.13556
Journal volume & issue
Vol. 8, no. 2

Abstract

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Infectious mononucleosis (IM), usually caused by Epstein-Barr virus (EBV), is not rare among populations. Fever, pharyngotonsilitis and lymphadenopathy are its major presentations. Since EBV mainly targets lymphomononuclear cells and the reticuloendothelial system, it might be mistaken with hematological malignancies. The case presented in this article showed a very high similarity to an acute lymphoblastic leukemia, which complicated the diagnostic work-up. The histopathological data and clinical course of IM patients are not usually distinctive; hence, early work-up for EBV-associated IM is suggested.

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