مجله علوم پزشکی فیض (پیوسته) (Mar 2024)

Comparison of the effects of high-intensity intermittent training and moderate-intensity continuous training on cardiometabolic factors in type 2 diabetic patients: a systematic review and meta-analysis

  • Fatemeh Kazemi Nesab,
  • Omid Zafarmand

Journal volume & issue
Vol. 28, no. 1
pp. 96 – 109

Abstract

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Background and Aim: Lifestyle interventions, including various types of exercise, are considered beneficial in managing type 2 diabetes. This systematic review and meta-analysis aimed at comparing the effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on cardiometabolic factors in type 2 diabetes. Methods: A systematic search of English and Farsi papers published in PubMed, Web of Science, Scopus, SID, and Magiran databases was conducted until August 2023. The search utilized keywords such as "high-intensity interval training (HIIT)", "moderate-intensity continuous exercise (MICT)", "cardiometabolic factors", and "type 2 diabetes". A meta-analysis was performed to compare the impact of HIIT and MICT training on cardiometabolic factors in type 2 diabetes. Mean differences and 95% confidence intervals (CI) were calculated using a random-effects model. Heterogeneity was assessed using the I2 test, and publication bias was evaluated through the visual analysis of funnel plots and Egger's test. Results: Analysis of 10 studies comprising 11 sports interventions involving 271 individuals with type 2 diabetes revealed that HIIT led to a significant reduction in fasting insulin [SMD=-0.93 (-1.25 to -0.6), P=0.001], HOMA-IR [WMD=-0.73 (-1.03 to -0.43), P=0.001], and systolic blood pressure [WMD=-3.15 mmHg (-6.29 to -0.01), P=0.04] compared to MICT in patients with type 2 diabetes. However, there were no significant differences in fasting glucose [WMD=-2.91 mg/dL (-7.97 to 2.14), P=0.2], diastolic blood pressure [WMD=0.3 mmHg (-0.77 to 1.56), P=0.5], and maximum oxygen consumption [SMD=0.49 (-0.004 to 0.99), P=0.05] between HIIT and MICT exercises in patients with type 2 diabetes. Conclusion: HIIT appears to be a favorable training method with efficient outcomes for improving cardiometabolic factors in patients with type 2 diabetes compared to MICT.

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