Hand osteoarthritis: pathogenesis, diagnosis, and approaches to therapy

Abstract

Osteoarthritis (OA) is a widespread disease accompanied by persistent joint damage with obvious functional failure, which leads to early disability in patients. In OA, different groups of joints are involved in the pathological process. Hand joints are one of the classical sites of OA. The paper discusses the role of mechanical load, genetic factors, and sex hormone deficiency in the development of the disease. The treatment policy includes a set of non-pharmacological, pharmacological, and surgical methods.

Keywords

• hand osteoarthritis
• nonsteroidal anti-inflammatory drugs
• capsaicin
• chondroitin sulfate
• glucosamine sulfate
• chondroguard
• sustaguard arthro
• vitamin d
• estrogen-containing drugs
• targeted therapy