Onset of vitiligo following contact dermatitis from eyeliner application in a 20-year-old female

Abstract

Vitiligo is an autoimmune condition characterized by the destruction of melanocytes, leading to depigmented skin patches. Allergic contact dermatitis, triggered by allergens in cosmetics, can initiate localized immune responses that may progress to systemic immune dysregulation in genetically predisposed individuals. This case explores the potential role of allergic contact dermatitis in triggering vitiligo and proposes mechanisms underlying this association.

Keywords

• Vitiligo
• eyelid depigmentation
• contact dermatitis
• Wood’s light examination
• cosmetic-induced vitiligo