Revista Peruana de Medicina Experimental y Salud Pública (Dec 2015)

Endemic Kaposi’s sarcoma in a HIV-negative patient

  • José Revilla-López,
  • Raúl Mendoza-Fabián,
  • Andrea Anampa-Guzmán,
  • Josias Rosales-Zúñiga,
  • Joel Chalco-Huamán

DOI
https://doi.org/10.17843/rpmesp.2015.324.1776
Journal volume & issue
Vol. 32, no. 4
pp. 808 – 812

Abstract

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Kaposi’s sarcoma (KS) is a multicentric, inflammatory angioproliferative cancer associated with herpes virus 8 (HHV-8). It has four clinico-epidemiological types: classic, endemic, iatrogenic and epidemic, or HIV associated. Clinically it may be indolent or aggressive, mainly affecting mucocutaneous areas with eventual visceral and lymph node involvement. It is often present and in a more aggressive form in the HIV-positive population. We report a case of a 27-year-old HIVnegative male patient with a bleeding tumoral lesion in the Waldeyer ring, multiple lymphadenopathies and exophytic foot lesions that remit with anthracycline-based emergency chemotherapy. HIV-negative KS is a rare condition. It is important to consider Peru as an endemic region for HHV-8. The oral involvement of KS is a rare manifestation and of poor prognosis, however, the HIV-negative factor could confer a good prognosis.

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