How to capture developmental brain dynamics: gaps and solutions

Abstract

Capturing developmental and learning-induced brain dynamics is extremely challenging as changes occur interactively across multiple levels and emerging functions. Different levels include the (social) environment, cognitive and behavioral levels, structural and functional brain changes, and genetics, while functions include domains such as math, reading, and executive function. Here, we report the insights that emerged from the workshop “Capturing Developmental Brain Dynamics”, organized to bring together multidisciplinary approaches to integrate data on development and learning across different levels, functions, and time points. During the workshop, current main gaps in our knowledge and tools were identified including the need for: (1) common frameworks, (2) longitudinal, large-scale, multisite studies using representative participant samples, (3) understanding interindividual variability, (4) explicit distinction of understanding versus predicting, and (5) reproducible research. After illustrating interactions across levels and functions during development, we discuss the identified gaps and provide solutions to advance the capturing of developmental brain dynamics.