A contribution to the therapeutic valorization of Moroccan Cistus Ladanifer L

Abstract

Cistus ladanifer L. is a medicinal shrub traditionally used against several diseases. The present study was performed for trying to enrich the potentialities of this plant by evaluating the possible analgaesic effect of aqueous extract of Cistus. ladanifer (AECL) and oral formulation prepared from AECL. The analgaesic effect was tested using the acetic acid induces writhing and formalin models. The results showed that both aqueous extract and herbal syrup induced a significant analgaesic activity in the two nociceptive tests. Moreover, the oral formulation produced the potent analgaesic effect. We conclude from the results of this work that the Moroccan C. ladanifer L orally administrated to mice possesses an efficient analgaesic effect, and may will contribute to developing a natural analgaesic drug.