AMB Express
(Jan 2023)
Production, characterization and techno-economic evaluation of Aspergillus fusant l-asparaginase
- Atim Asitok,
- Maurice Ekpenyong,
- Andrew Amenaghawon,
- Ernest Akwagiobe,
- Marcus Asuquo,
- Anitha Rao,
- David Ubi,
- Juliet Iheanacho,
- Joyce Etiosa,
- Agnes Antai,
- Joseph Essien,
- Sylvester Antai
Affiliations
- Atim Asitok
- Environmental Microbiology and Biotechnology Unit, Department of Microbiology, University of Calabar
- Maurice Ekpenyong
- Environmental Microbiology and Biotechnology Unit, Department of Microbiology, University of Calabar
- Andrew Amenaghawon
- Department of Chemical Engineering, University of Benin
- Ernest Akwagiobe
- Industrial Microbiology and Biotechnology Unit, Department of Microbiology, Faculty of Biological Sciences, University of Calabar
- Marcus Asuquo
- Department of Hematology, University of Calabar Teaching Hospital
- Anitha Rao
- Industrial Microbiology and Biotechnology Unit, Department of Microbiology, Faculty of Biological Sciences, University of Calabar
- David Ubi
- Industrial Microbiology and Biotechnology Unit, Department of Microbiology, Faculty of Biological Sciences, University of Calabar
- Juliet Iheanacho
- Environmental Microbiology and Biotechnology Unit, Department of Microbiology, University of Calabar
- Joyce Etiosa
- Environmental Microbiology and Biotechnology Unit, Department of Microbiology, University of Calabar
- Agnes Antai
- Department of Economics, Faculty of Social Sciences, University of Calabar
- Joseph Essien
- Department of Microbiology, Faculty of Science, University of Uyo
- Sylvester Antai
- Environmental Microbiology and Biotechnology Unit, Department of Microbiology, University of Calabar
- DOI
-
https://doi.org/10.1186/s13568-022-01505-8
- Journal volume & issue
-
Vol. 13,
no. 1
pp.
1
– 18
Abstract
Read online
Key points Sensitivity analysis confirmed optimization conditions for ATPS L-ASNase recovery Fed-batch fermentation outperformed other modes in techno-economic evaluations Fusant improved clinical and industrial characteristics indicate recombination success
Keywords
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