Communications Biology (Sep 2022)

Hybrid metagenome assemblies link carbohydrate structure with function in the human gut microbiome

  • Anuradha Ravi,
  • Perla Troncoso-Rey,
  • Jennifer Ahn-Jarvis,
  • Kendall R. Corbin,
  • Suzanne Harris,
  • Hannah Harris,
  • Alp Aydin,
  • Gemma L. Kay,
  • Thanh Le Viet,
  • Rachel Gilroy,
  • Mark J. Pallen,
  • Andrew J. Page,
  • Justin O’Grady,
  • Frederick J. Warren

DOI
https://doi.org/10.1038/s42003-022-03865-0
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 13

Abstract

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Longitudinal hybrid metagenomic analyses of a human stool sample reveal compositional and functional variation in response to six structurally-distinct carbohydrates, providing insight into how gut bacteria utilize various carbohydrate sources.