Педиатрическая фармакология (Jun 2019)

Loop tubulopathies: Bartter’s syndrome

  • Alexander A. Baranov,
  • Leyla S. Namazova-Baranova,
  • Tatyana V. Sergeeva,
  • Olga V. Chumakova,
  • Svetlana S. Paunova,
  • Nurali Z. Zokirov,
  • Olga V. Komarova,
  • Tea V. Margieva,
  • Vladimir K. Tatochenko,
  • Maya D. Bakradze,
  • Elena N. Tsygina,
  • Olga I. Zrobok,
  • Tatiana V. Vashurina,
  • Irina N. Lupan,
  • Mikhail Yu. Kagan,
  • Alexey N. Tsygin

DOI
https://doi.org/10.15690/pf.v16i2.2004
Journal volume & issue
Vol. 16, no. 2
pp. 85 – 90

Abstract

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The authors provide a review of current clinical guidelines regarding medical care provided to children with Bartter’s syndrome — impaired renal tubular function (loop of Henle) with the development of hypokalemia, hypochloremia, metabolic alkalosis and hyperreninemic hyperaldosteronism. The specifics of disease epidemiology, etiology and pathogenesis are described. The issues of differential diagnosis and treatment based on the principles of evidence are covered.

Keywords