Scientific Reports (May 2021)

Modular barcode beads for microfluidic single cell genomics

  • Cyrille L. Delley,
  • Adam R. Abate

DOI
https://doi.org/10.1038/s41598-021-90255-x
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 9

Abstract

Read online

Abstract Barcode beads allow efficient nucleic acid tagging in single cell genomics. Current barcode designs, however, are fabricated with a particular application in mind. Repurposing to novel targets, or altering to add additional targets as information is obtained is possible but the result is suboptimal. Here, we describe a modular framework that simplifies generation of multifunctional beads and allows their easy extension to new targets.