Cellular Oncology (Jan 2010)

A Virtual Microscopy System to Scan, Evaluate and Archive Biomarker Enhanced Cervical Cytology Slides

  • Niels Grabe,
  • Bernd Lahrmann,
  • Thora Pommerencke,
  • Magnus von Knebel Doeberitz,
  • Miriam Reuschenbach,
  • Nicolas Wentzensen

DOI
https://doi.org/10.3233/CLO-2009-0508
Journal volume & issue
Vol. 32, no. 1-2
pp. 109 – 119

Abstract

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Background: Although cytological screening for cervical precancers has led to a reduction of cervical cancer incidence worldwide it is a subjective and variable method with low single-test sensitivity. New biomarkers like p16 that specifically highlight abnormal cervical cells can improve cytology performance. Virtual microscopy offers an ideal platform for assisted evaluation and archiving of biomarker-stained slides.