eLife (Aug 2020)

A systematic review of population-based studies on lipid profiles in Latin America and the Caribbean

  • Rodrigo M Carrillo-Larco,
  • C Joel Benites-Moya,
  • Cecilia Anza-Ramirez,
  • Leonardo Albitres-Flores,
  • Diana Sánchez-Velazco,
  • Niels Pacheco-Barrios,
  • Antonio Bernabe-Ortiz

DOI
https://doi.org/10.7554/eLife.57980
Journal volume & issue
Vol. 9

Abstract

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We aimed to study time trends and levels of mean total cholesterol and lipid fractions, and dyslipidaemias prevalence in Latin America and the Caribbean (LAC). Systematic-review and meta-analysis of population-based studies in which lipid (total cholesterol [TC; 86 studies; 168,553 people], HDL-Cholesterol [HDL-C; 84 studies; 121,282 people], LDL-Cholesterol [LDL-C; 61 studies; 86,854 people], and triglycerides [TG; 84 studies; 121,009 people]) levels and prevalences were laboratory-based. We used Scopus, LILACS, Embase, Medline and Global Health; studies were from 1964 to 2016. Pooled means and prevalences were estimated for lipid biomarkers from ≥2005. The pooled means (mg/dl) were 193 for TC, 120 for LDL-C, 47 for HDL-C, and 139 for TG; no strong trends. The pooled prevalence estimates were 21% for high TC, 20% for high LDL-C, 48% for low HDL-C, and 21% for high TG; no strong trends. These results may help strengthen programs for dyslipidaemias prevention/management in LAC.

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