Mechanistic Modeling of Reversed-Phase Chromatography of Insulins with Potassium Chloride and Ethanol as Mobile-Phase Modulators

• Karolina Arkell,
• Martin P. Breil,
• Søren S. Frederiksen,
• Bernt Nilsson

Affiliations

Karolina Arkell

Department of Chemical Engineering, Faculty of Engineering, Lund University, Lund, Sweden

Martin P. Breil

‡Modelling and Optimization, Novo Nordisk A/S, Bagsværd, Denmark

Søren S. Frederiksen

§Mathematical Modelling, Novo Nordisk A/S, Bagsværd, Denmark

Bernt Nilsson

Department of Chemical Engineering, Faculty of Engineering, Lund University, Lund, Sweden