Sarcoma
(Jan 2000)
Proliferative Activity (Ki-67 Expression) and Outcome in High Grade
Osteosarcoma: A Study of 27 Cases
Roland Jong,
Aileen M. Davis,
Maria G. Mendes,
Jay S. Wunder,
Robert S. Bell,
Rita Kandel
Affiliations
Roland Jong
Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, University of Toronto, Toronto M5G 1X5, Ontario, Canada
Aileen M. Davis
University Musculoskeletal Oncology Unit, Mount Sinai Hospital, University of Toronto, Toronto M5G 1X5, Ontario, Canada
Maria G. Mendes
Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, University of Toronto, Toronto M5G 1X5, Ontario, Canada
Jay S. Wunder
University Musculoskeletal Oncology Unit, Mount Sinai Hospital, University of Toronto, Toronto M5G 1X5, Ontario, Canada
Robert S. Bell
University Musculoskeletal Oncology Unit, Mount Sinai Hospital, University of Toronto, Toronto M5G 1X5, Ontario, Canada
Rita Kandel
Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, University of Toronto, Toronto M5G 1X5, Ontario, Canada
DOI
https://doi.org/10.1155/S1357714X00000086
Journal volume & issue
Vol. 4,
no. 1-2
Abstract
Read online
Purpose. Although pre-operative chemotherapy has improved the prognosis for individuals with osteosarcoma, approximately 40% of patients will die of their disease.The aim of this study was to quantitate proliferative activity in high grade osteosarcomas and to determine whether proliferation is a prognostic factor.
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