Nature Communications (Jul 2022)

Lactational delivery of Triclosan promotes non-alcoholic fatty liver disease in newborn mice

  • André A. Weber,
  • Xiaojing Yang,
  • Elvira Mennillo,
  • Jeffrey Ding,
  • Jeramie D. Watrous,
  • Mohit Jain,
  • Shujuan Chen,
  • Michael Karin,
  • Robert H. Tukey

DOI
https://doi.org/10.1038/s41467-022-31947-4
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 13

Abstract

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Triclosan is an antimicrobial additive in consumer products that has been detected in human breast milk. Here the authors report that exposure of pregnant mice to triclosan leads to lactational exposure to newborns and the development of liver steatosis.