Journal of Mazandaran University of Medical Sciences (Nov 2023)
Study of Complete Blood Count Variables at Birth in Preterm Infants with Intraventricular Hemorrhage (IVH) in Bouali Sina and Imam Khomeini Hospital, Sari from 1395 to 1398
Abstract
Background and purpose: Intraventricular hemorrhage (IVH) is known as a major complication of Prematurity. In this study, we aimed to examine complete blood count (CBC) variables in preterm infants with IVH. Materials and methods: In this cross-sectional descriptive study, we studied preterm infants less than or equal to 34 weeks and less than 1500 g admitted to the NICU and neonatal ward of Bu Ali Sina and Imam Khomeini hospitals in Sari from 1395 to 1398. The presence of IVH in brain ultrasonography was recorded in these neonates. Results: Out of 367 neonates, 49.05% were boys and 50.95% were girls. The mean gestational age was 30.96±2.30 weeks and the mean weight of the patients was 1461±504.99 g. 41 patients (11.17%) had intraventricular hemorrhage. Infants with a history of maternal diabetes were more common in the group with intraventricular hemorrhage (P= 0.042). Mean hemoglobin, MCV and MCH were significantly higher in the group with ventricular hemorrhage and mean CRP and blood glucose were higher in this group (P<0.05). The results of logistic regression model showed that Higher blood sugar in the newborn, history of diabetes in the mother, history of receiving surfactant in the newborn, and lower MCH and MCV in the newborn baby's CBC were significantly effective in he chance of intraventricular hemorrhage (P<0.05). Also, hemoglobin and MCH were significantly lower in grades 2, 3 and 4 than grade 1of IVH. Conclusion: Results of the present study showed that Microcytic hypochromic anemia can be used to predict the occurrence of IVH.
