Nature Communications (Aug 2019)

Synthetic molecular recognition nanosensor paint for microalbuminuria

  • Januka Budhathoki-Uprety,
  • Janki Shah,
  • Joshua A. Korsen,
  • Alysandria E. Wayne,
  • Thomas V. Galassi,
  • Joseph R. Cohen,
  • Jackson D. Harvey,
  • Prakrit V. Jena,
  • Lakshmi V. Ramanathan,
  • Edgar A. Jaimes,
  • Daniel A. Heller

DOI
https://doi.org/10.1038/s41467-019-11583-1
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 9

Abstract

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Microalbuminuria, a clinical marker associated with cancer and hypertension, defined by low albumin levels in the urine, is normally detected by immunoassay. Herein, a nanosensor paint was developed using a polymer to mimic fatty acid binding to albumin, transduced by carbon nanotube fluorescence.