Nature Communications (Mar 2023)
MYC reshapes CTCF-mediated chromatin architecture in prostate cancer
- Zhao Wei,
- Song Wang,
- Yaning Xu,
- Wenzheng Wang,
- Fraser Soares,
- Musaddeque Ahmed,
- Ping Su,
- Tingting Wang,
- Elias Orouji,
- Xin Xu,
- Yong Zeng,
- Sujun Chen,
- Xiaoyu Liu,
- Tianwei Jia,
- Zhaojian Liu,
- Lutao Du,
- Yunshan Wang,
- Shaoyong Chen,
- Chuanxin Wang,
- Housheng Hansen He,
- Haiyang Guo
Affiliations
- Zhao Wei
- Department of Clinical Laboratory, Qilu Hospital of Shandong University
- Song Wang
- Department of Clinical Laboratory, the Second Hospital, Cheeloo College of Medicine, Shandong University
- Yaning Xu
- Department of Clinical Laboratory, the Second Hospital, Cheeloo College of Medicine, Shandong University
- Wenzheng Wang
- Department of Clinical Laboratory, the Second Hospital, Cheeloo College of Medicine, Shandong University
- Fraser Soares
- Princess Margaret Cancer Center/University Health Network
- Musaddeque Ahmed
- Princess Margaret Cancer Center/University Health Network
- Ping Su
- National Administration of Health Data
- Tingting Wang
- Institute of Medical Sciences, the Second Hospital, Cheeloo College of Medicine, Shandong University
- Elias Orouji
- Epigenetics Initiative, Princess Margaret Genomics Centre
- Xin Xu
- Princess Margaret Cancer Center/University Health Network
- Yong Zeng
- Princess Margaret Cancer Center/University Health Network
- Sujun Chen
- Princess Margaret Cancer Center/University Health Network
- Xiaoyu Liu
- Department of Clinical Laboratory, the Second Hospital, Cheeloo College of Medicine, Shandong University
- Tianwei Jia
- Department of Clinical Laboratory, the Second Hospital, Cheeloo College of Medicine, Shandong University
- Zhaojian Liu
- Key Laboratory of Experimental Teratology, Ministry of Education, Department of Cell Biology, Cheeloo College of Medicine, Shandong University
- Lutao Du
- Department of Clinical Laboratory, the Second Hospital, Cheeloo College of Medicine, Shandong University
- Yunshan Wang
- Department of Clinical Laboratory, the Second Hospital, Cheeloo College of Medicine, Shandong University
- Shaoyong Chen
- Hematology-Oncology Division, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School
- Chuanxin Wang
- Department of Clinical Laboratory, the Second Hospital, Cheeloo College of Medicine, Shandong University
- Housheng Hansen He
- Princess Margaret Cancer Center/University Health Network
- Haiyang Guo
- Department of Clinical Laboratory, the Second Hospital, Cheeloo College of Medicine, Shandong University
- DOI
- https://doi.org/10.1038/s41467-023-37544-3
- Journal volume & issue
-
Vol. 14,
no. 1
pp. 1 – 15
Abstract
The functional link between MYC and CTCF in prostate cancer remains to be investigated. Here, the authors highlight the role of MYC in rewiring chromatin architecture by interacting with CTCF protein.
