The psychosis human connectome project: An overview
Caroline Demro,
Bryon A. Mueller,
Jerillyn S. Kent,
Philip C. Burton,
Cheryl A. Olman,
Michael-Paul Schallmo,
Kelvin O. Lim,
Scott R. Sponheim
Affiliations
Caroline Demro
Department of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, MN, United States; Department of Psychology, University of Minnesota, Minneapolis, MN, United State
Bryon A. Mueller
Department of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, MN, United States
Jerillyn S. Kent
Department of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, MN, United States
Philip C. Burton
College of Liberal Arts, University of Minnesota, Minneapolis, MN, United State
Cheryl A. Olman
Department of Psychology, University of Minnesota, Minneapolis, MN, United State
Michael-Paul Schallmo
Department of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, MN, United States
Kelvin O. Lim
Department of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, MN, United States; Minneapolis Veterans Affairs Medical Center, 1 Veterans Drive, Minneapolis, MN 55417, United State
Scott R. Sponheim
Department of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, MN, United States; Department of Psychology, University of Minnesota, Minneapolis, MN, United State; Minneapolis Veterans Affairs Medical Center, 1 Veterans Drive, Minneapolis, MN 55417, United State; Corresponding author at: Minneapolis Veterans Affairs Health Care System, 1 Veterans Dr, Minneapolis, MN 55417, USA.
Investigations within the Human Connectome Project have expanded to include studies focusing on brain disorders. This paper describes one of the investigations focused on psychotic psychopathology: The psychosis Human Connectome Project (P-HCP). The data collected as part of this project were multimodal and derived from clinical assessments of psychopathology, cognitive assessments, instrument-based motor assessments, blood specimens, and magnetic resonance imaging (MRI) data. The dataset will be made publicly available through the NIMH Data Archive. In this report we provide specific information on how the sample of participants was obtained and characterized and describe the experimental tasks and procedures used to probe neural functions involved in psychotic disorders that may also mark genetic liability for psychotic psychopathology. Our goal in this paper is to outline the data acquisition process so that researchers intending to use these publicly available data can plan their analyses. MRI data described in this paper are limited to data acquired at 3 Tesla. A companion paper describes the study's 7 Tesla image acquisition protocol in detail, which is focused on visual perceptual functions in psychotic psychopathology.
