Tropical Medicine and Infectious Disease (Mar 2018)
Melioidosis in Singapore: Clinical, Veterinary, and Environmental Perspectives
- Siew Hoon Sim,
- Catherine Ee Ling Ong,
- Yunn Hwen Gan,
- Dongling Wang,
- Victor Wee Hong Koh,
- Yian Kim Tan,
- Michelle Su Yen Wong,
- Janet Seok Wei Chew,
- Sian Foong Ling,
- Brian Zi Yan Tan,
- Agnes Zhengyu Ye,
- Patrick Chuan Kiat Bay,
- Wai Kwan Wong,
- Charlene Judith Fernandez,
- Shangzhe Xie,
- Praveena Jayarajah,
- Tasha Tahar,
- Pei Yee Oh,
- Sonja Luz,
- Jaime Mei Fong Chien,
- Thuan Tong Tan,
- Louis Yi Ann Chai,
- Dale Fisher,
- Yichun Liu,
- Jimmy Jin Phang Loh,
- Gladys Gek Yen Tan
Affiliations
- Siew Hoon Sim
- Defence Medical and Environmental Research Institute, DSO National Laboratories, Singapore 117510, Singapore
- Catherine Ee Ling Ong
- Defence Medical and Environmental Research Institute, DSO National Laboratories, Singapore 117510, Singapore
- Yunn Hwen Gan
- Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore
- Dongling Wang
- Defence Medical and Environmental Research Institute, DSO National Laboratories, Singapore 117510, Singapore
- Victor Wee Hong Koh
- Defence Medical and Environmental Research Institute, DSO National Laboratories, Singapore 117510, Singapore
- Yian Kim Tan
- Defence Medical and Environmental Research Institute, DSO National Laboratories, Singapore 117510, Singapore
- Michelle Su Yen Wong
- Defence Medical and Environmental Research Institute, DSO National Laboratories, Singapore 117510, Singapore
- Janet Seok Wei Chew
- Defence Medical and Environmental Research Institute, DSO National Laboratories, Singapore 117510, Singapore
- Sian Foong Ling
- Defence Medical and Environmental Research Institute, DSO National Laboratories, Singapore 117510, Singapore
- Brian Zi Yan Tan
- Laboratories Group, Agri-Food & Veterinary Authority of Singapore, Singapore 718827, Singapore
- Agnes Zhengyu Ye
- Laboratories Group, Agri-Food & Veterinary Authority of Singapore, Singapore 718827, Singapore
- Patrick Chuan Kiat Bay
- Food Establishment Regulation Group, Agri-Food & Veterinary Authority of Singapore, Singapore 608550, Singapore
- Wai Kwan Wong
- Laboratories Group, Agri-Food & Veterinary Authority of Singapore, Singapore 718827, Singapore
- Charlene Judith Fernandez
- Laboratories Group, Agri-Food & Veterinary Authority of Singapore, Singapore 718827, Singapore
- Shangzhe Xie
- Conservation, Research and Veterinary Services, Wildlife Reserves Singapore, Singapore 729826, Singapore
- Praveena Jayarajah
- Conservation, Research and Veterinary Services, Wildlife Reserves Singapore, Singapore 729826, Singapore
- Tasha Tahar
- Conservation, Research and Veterinary Services, Wildlife Reserves Singapore, Singapore 729826, Singapore
- Pei Yee Oh
- Conservation, Research and Veterinary Services, Wildlife Reserves Singapore, Singapore 729826, Singapore
- Sonja Luz
- Conservation, Research and Veterinary Services, Wildlife Reserves Singapore, Singapore 729826, Singapore
- Jaime Mei Fong Chien
- Department of Infectious Diseases, Singapore General Hospital, Singapore 169608, Singapore
- Thuan Tong Tan
- Department of Infectious Diseases, Singapore General Hospital, Singapore 169608, Singapore
- Louis Yi Ann Chai
- Division of Infectious Diseases, Department of Medicine, National University Health System, Singapore 119228, Singapore
- Dale Fisher
- Division of Infectious Diseases, Department of Medicine, National University Health System, Singapore 119228, Singapore
- Yichun Liu
- Defence Medical and Environmental Research Institute, DSO National Laboratories, Singapore 117510, Singapore
- Jimmy Jin Phang Loh
- Defence Medical and Environmental Research Institute, DSO National Laboratories, Singapore 117510, Singapore
- Gladys Gek Yen Tan
- Defence Medical and Environmental Research Institute, DSO National Laboratories, Singapore 117510, Singapore
- DOI
- https://doi.org/10.3390/tropicalmed3010031
- Journal volume & issue
-
Vol. 3,
no. 1
p. 31
Abstract
Melioidosis is a notifiable infectious disease registered with the Ministry of Health (MOH) and Agri-Food & Veterinary Authority (AVA), Singapore. From a clinical perspective, increased awareness of the disease has led to early detection and treatment initiation, thus resulting in decreasing mortality rates in recent years. However, the disease still poses a threat to local pet, zoo and farm animals, where early diagnosis is a challenge. The lack of routine environmental surveillance studies also makes prevention of the disease in animals difficult. To date, there have been no reports that provide a complete picture of how the disease impacts the local human and animal populations in Singapore. Information on the distribution of Burkholderia pseudomallei in the environment is also lacking. The aim of this review is to provide a comprehensive overview of both published and unpublished clinical, veterinary and environmental studies on melioidosis in Singapore to achieve better awareness and management of the disease.
Keywords
