Nature Communications (Jul 2022)
Differential neutralization and inhibition of SARS-CoV-2 variants by antibodies elicited by COVID-19 mRNA vaccines
- Li Wang,
- Markus H. Kainulainen,
- Nannan Jiang,
- Han Di,
- Gaston Bonenfant,
- Lisa Mills,
- Michael Currier,
- Punya Shrivastava-Ranjan,
- Brenda M. Calderon,
- Mili Sheth,
- Brian R. Mann,
- Jaber Hossain,
- Xudong Lin,
- Sandra Lester,
- Elizabeth A. Pusch,
- Joyce Jones,
- Dan Cui,
- Payel Chatterjee,
- M. Harley Jenks,
- Esther K. Morantz,
- Gloria P. Larson,
- Masato Hatta,
- Jennifer L. Harcourt,
- Azaibi Tamin,
- Yan Li,
- Ying Tao,
- Kun Zhao,
- Kristine Lacek,
- Ashley Burroughs,
- Wei Wang,
- Malania Wilson,
- Terianne Wong,
- So Hee Park,
- Suxiang Tong,
- John R. Barnes,
- Mark W. Tenforde,
- Wesley H. Self,
- Nathan I. Shapiro,
- Matthew C. Exline,
- D. Clark Files,
- Kevin W. Gibbs,
- David N. Hager,
- Manish Patel,
- Alison L. Halpin,
- Laura K. McMullan,
- Justin S. Lee,
- Hongjie Xia,
- Xuping Xie,
- Pei-Yong Shi,
- C. Todd Davis,
- Christina F. Spiropoulou,
- Natalie J. Thornburg,
- M. Steven Oberste,
- Vivien G. Dugan,
- SSEV Bioinformatics Working Group,
- David E. Wentworth,
- Bin Zhou
Affiliations
- Li Wang
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Markus H. Kainulainen
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Nannan Jiang
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Han Di
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Gaston Bonenfant
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Lisa Mills
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Michael Currier
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Punya Shrivastava-Ranjan
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Brenda M. Calderon
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Mili Sheth
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Brian R. Mann
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Jaber Hossain
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Xudong Lin
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Sandra Lester
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Elizabeth A. Pusch
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Joyce Jones
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Dan Cui
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Payel Chatterjee
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- M. Harley Jenks
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Esther K. Morantz
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Gloria P. Larson
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Masato Hatta
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Jennifer L. Harcourt
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Azaibi Tamin
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Yan Li
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Ying Tao
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Kun Zhao
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Kristine Lacek
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Ashley Burroughs
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Wei Wang
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Malania Wilson
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Terianne Wong
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- So Hee Park
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Suxiang Tong
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- John R. Barnes
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Mark W. Tenforde
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Wesley H. Self
- Vanderbilt University
- Nathan I. Shapiro
- Harvard University
- Matthew C. Exline
- Ohio State University
- D. Clark Files
- Wake Forest Baptist Medical Center
- Kevin W. Gibbs
- Wake Forest Baptist Medical Center
- David N. Hager
- Johns Hopkins University
- Manish Patel
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Alison L. Halpin
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Laura K. McMullan
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Justin S. Lee
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Hongjie Xia
- University of Texas Medical Branch
- Xuping Xie
- University of Texas Medical Branch
- Pei-Yong Shi
- University of Texas Medical Branch
- C. Todd Davis
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Christina F. Spiropoulou
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Natalie J. Thornburg
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- M. Steven Oberste
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Vivien G. Dugan
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- SSEV Bioinformatics Working Group
- David E. Wentworth
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- Bin Zhou
- COVID-19 Emergency Response, Centers for Disease Control and Prevention
- DOI
- https://doi.org/10.1038/s41467-022-31929-6
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 10
Abstract
Emerging SARS-CoV-2 variants raise concerns on immune evasion. Here, the authors evaluate the neutralization efficiency of COVID-19 mRNA vaccinee sera against representative viruses of 13 WHO-designated SARS-CoV-2 variants of concern/interest.
