Nature Communications (Aug 2022)
Engineering micro oxygen factories to slow tumour progression via hyperoxic microenvironments
- Weili Wang,
- Huizhen Zheng,
- Jun Jiang,
- Zhi Li,
- Dongpeng Jiang,
- Xiangru Shi,
- Hui Wang,
- Jie Jiang,
- Qianqian Xie,
- Meng Gao,
- Jianhong Chu,
- Xiaoming Cai,
- Tian Xia,
- Ruibin Li
Affiliations
- Weili Wang
- State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Suzhou Medical College, Soochow University
- Huizhen Zheng
- State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Suzhou Medical College, Soochow University
- Jun Jiang
- State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Suzhou Medical College, Soochow University
- Zhi Li
- Department of Interventional Radiology, the First Affiliated Hospital of Soochow University, Soochow University
- Dongpeng Jiang
- Institute of Blood and Marrow Transplantation, National Clinical Research Center for Hematologic Diseases, Soochow University
- Xiangru Shi
- Institute of Blood and Marrow Transplantation, National Clinical Research Center for Hematologic Diseases, Soochow University
- Hui Wang
- State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Suzhou Medical College, Soochow University
- Jie Jiang
- State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Suzhou Medical College, Soochow University
- Qianqian Xie
- State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Suzhou Medical College, Soochow University
- Meng Gao
- State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Suzhou Medical College, Soochow University
- Jianhong Chu
- Institute of Blood and Marrow Transplantation, National Clinical Research Center for Hematologic Diseases, Soochow University
- Xiaoming Cai
- School of Public Health, Suzhou Medical College, Soochow University
- Tian Xia
- Division of NanoMedicine, Department of Medicine, California Nanosystems Institute, University of California
- Ruibin Li
- State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Suzhou Medical College, Soochow University
- DOI
- https://doi.org/10.1038/s41467-022-32066-w
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 17
Abstract
Tumour hypoxia is an important factor in tumorigenesis and cancer therapy. Here, the authors present a micro oxygenation factory, capable of providing an oxygen supply through photosynthesis, and demonstrate its utility in cancer therapy.
