The effects of two types of interval training on the association between cardiovascular fitness and atherogenic biomarkers with blood pressure in wWomen with overweight/obesity

Abstract

Background and Purpose: Obesity, especially central body obesity, is related to cardiovascular diseases risk factors such as high blood pressure and hyperlipidemia. The aim of the present study was to investigate the relationship between blood pressure and serum levels of salusin-β, angiopoietin-like protein 3, lipid profile and anthropometric indicators following eight weeks of interval training with different intensities among women with overweight/obesity. Materials and Methods: In this study, 30 inactive women were divided into three groups of 10 including control group (average age, 28.7 years; body mass index, 30.42±3.29 kg/m2), moderate-intensity interval training group (average age, 30.2 years; body mass index, 31.19 ±3.75 kg/m2), and high-intensity interval training group (average age, 28.9 years ؛body mass index, 30.17 ±3.83 kg/m2). The Subjects in training groups performed eight weeks of interval training encompassed pedaling on a stationary bike with different intensities. Blood samples were taken 48 hours before the first training session (baseline values) and 48 hours after the last training session to measure the serum levels of salusin-β, angiopoietin-like protein 3 by using ELISA method. Factorial ANOVA and Pearson's correlation coefficient tests were used to analyze the data. Results: Data analysis showed a positive and significant relationship (P<0.05) between blood pressure and angiopoietin-like protein 3, waist-hip ratio, salusin-β, waist circumference and an inverse significant relationship between blood pressure and high density lipoproteins (P<0.05). Factorial analysis of variance showed a significant decrease in the levels of angiopoietin-like protein 3, salusin-β, triglyceride, weight, waist circumference, waist-stature ratio, body mass index, systolic blood pressure and a significant increase in the levels of high-density lipoproteins following eight weeks of interval training (P<0.05). However, no significant changes were observed for low-density lipoproteins, diastolic blood pressure and waist-hip ratio following interval training. Conclusion: Interval training with sufficient intensity can be effective in increasing obese/overweight individuals’ health by improving body composition and reducing some serum proteins related to high blood pressure.

Keywords

• exercise
• angiopoietin-like protein 3
• salusin-beta
• obesity