Creating complex protocells and prototissues using simple DNA building blocks

Nishkantha Arulkumaran; Mervyn Singer; Stefan Howorka; Jonathan R. Burns

doi:10.1038/s41467-023-36875-5

Nature Communications (Mar 2023)

Creating complex protocells and prototissues using simple DNA building blocks

Nishkantha Arulkumaran,
Mervyn Singer,
Stefan Howorka,
Jonathan R. Burns

Affiliations

Nishkantha Arulkumaran: Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London
Mervyn Singer: Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London
Stefan Howorka: Department of Chemistry, Institute of Structural and Molecular Biology, University Collegfige London
Jonathan R. Burns: Department of Chemistry, Institute of Structural and Molecular Biology, University Collegfige London

DOI: https://doi.org/10.1038/s41467-023-36875-5
Journal volume & issue: Vol. 14, no. 1
pp. 1 – 13

Abstract

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Building synthetic protocells and prototissues hinges on the formation of biomimetic skeletal frameworks. Here, the authors harness simplicity to create complexity by assembling DNA subunits into structural frameworks which support membrane-based protocells and prototissues.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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