Increased Levels of Airway Neutrophils Reduces the Inhibitory Effects of Inhaled Glucocorticosteroids on Allergen-Induced Airway Eosinophils

Gail M Gauvreau; Mark D Inman; Margaret Kelly; Richard M Watson; Sandra C Dorman; Paul M O’Byrne

doi:10.1155/2002/161969

Canadian Respiratory Journal (Jan 2002)

Increased Levels of Airway Neutrophils Reduces the Inhibitory Effects of Inhaled Glucocorticosteroids on Allergen-Induced Airway Eosinophils

Gail M Gauvreau,
Mark D Inman,
Margaret Kelly,
Richard M Watson,
Sandra C Dorman,
Paul M O’Byrne

Affiliations

Gail M Gauvreau: Asthma Research Group, McMaster University, Hamilton, Ontario, McMaster University, Hamilton, Ontario, Canada
Mark D Inman: Asthma Research Group, McMaster University, Hamilton, Ontario, McMaster University, Hamilton, Ontario, Canada
Margaret Kelly: Asthma Research Group, McMaster University, Hamilton, Ontario, McMaster University, Hamilton, Ontario, Canada
Richard M Watson: Asthma Research Group, McMaster University, Hamilton, Ontario, McMaster University, Hamilton, Ontario, Canada
Sandra C Dorman: Asthma Research Group, McMaster University, Hamilton, Ontario, McMaster University, Hamilton, Ontario, Canada
Paul M O’Byrne: Asthma Research Group, McMaster University, Hamilton, Ontario, McMaster University, Hamilton, Ontario, Canada

DOI: https://doi.org/10.1155/2002/161969
Journal volume & issue: Vol. 9, no. 1
pp. 26 – 32

Abstract

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BACKGROUND: Treatment with inhaled glucocorticosteroids attenuates allergen-induced airway inflammation but is less effective in people with asthma who have noneosinophilic airway inflammation.

Published in Canadian Respiratory Journal

ISSN: 1198-2241 (Print); 1916-7245 (Online)
Publisher: Hindawi Limited
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the respiratory system
Website: https://www.hindawi.com/journals/crj/

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