Menelloides C and D, New Sesquiterpenoids from the Gorgonian Coral Menella sp.

Abstract

Two new metabolites, including a lindenane-type sesquiterpenoid, menelloide C (1), and a germacrane-type sesquiterpenoid, menelloide D (2), were isolated from a Formosan gorgonian coral identified as Menella sp. The structures of 1 and 2 were established by spectroscopic methods and 2 displayed a weak inhibitory effect on the release of elastase by human neutrophils.

Keywords

• menelloide
• lindenane
• germacrane
• sesquiterpenoid
• Menella
• elastase