A case of community-acquired Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus (MRSA) necrotizing pneumonia successfully treated with two anti-MRSA drugs

Ritsuya Shiiba; Masahiro Sano; Yoshihito Kogure; Hiroto Murao; Yuki Takigawa; Atsushi Torii; Arisa Yamada; Yuka Shinohara; Hideyuki Niwa; Chiyoe Kitagawa; Masahide Oki

Respiratory Medicine Case Reports (Jan 2024)

A case of community-acquired Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus (MRSA) necrotizing pneumonia successfully treated with two anti-MRSA drugs

Ritsuya Shiiba,
Masahiro Sano,
Yoshihito Kogure,
Hiroto Murao,
Yuki Takigawa,
Atsushi Torii,
Arisa Yamada,
Yuka Shinohara,
Hideyuki Niwa,
Chiyoe Kitagawa,
Masahide Oki

Affiliations

Ritsuya Shiiba: Corresponding author. Department of Respiratory Medicine, National Hospital Organization Nagoya Medical Center, 4-1-1, Sannomaru, Naka-ku, Nagoya 460-0001, Japan.; Department of Respiratory Medicine, NHO Nagoya Medical Center, Nagoya, Japan
Masahiro Sano: Department of Respiratory Medicine, NHO Nagoya Medical Center, Nagoya, Japan
Yoshihito Kogure: Department of Respiratory Medicine, NHO Nagoya Medical Center, Nagoya, Japan
Hiroto Murao: Department of Respiratory Medicine, NHO Nagoya Medical Center, Nagoya, Japan
Yuki Takigawa: Department of Respiratory Medicine, NHO Nagoya Medical Center, Nagoya, Japan
Atsushi Torii: Department of Respiratory Medicine, NHO Nagoya Medical Center, Nagoya, Japan
Arisa Yamada: Department of Respiratory Medicine, NHO Nagoya Medical Center, Nagoya, Japan
Yuka Shinohara: Department of Respiratory Medicine, NHO Nagoya Medical Center, Nagoya, Japan
Hideyuki Niwa: Department of Respiratory Medicine, NHO Nagoya Medical Center, Nagoya, Japan
Chiyoe Kitagawa: Department of Respiratory Medicine, NHO Nagoya Medical Center, Nagoya, Japan
Masahide Oki: Department of Respiratory Medicine, NHO Nagoya Medical Center, Nagoya, Japan

Journal volume & issue: Vol. 49
p. 102023

Abstract

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A 22-year-old Vietnamese man was referred to our hospital owing to cough, dyspnea, and difficulty moving. The patient was diagnosed with community-acquired Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus (MRSA) bacteremia and necrotizing pneumonia. Treatment involved vancomycin (VCM) and meropenem, and the MRSA bacteremia improved. However, lung tissue destruction progressed. Therefore, linezolid was added to the VCM regimen, and this intervention led to the patient's recovery, and he was discharged from the hospital. Here, we report a case in which the patient was treated with a combination of two anti-MRSA drugs and was cured.

Published in Respiratory Medicine Case Reports

ISSN: 2213-0071 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the respiratory system
Website: http://www.journals.elsevier.com/respiratory-medicine-case-reports/

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