Effect of <i>Artemisia absinthium</i> and <i>Malva sylvestris</i> on Antioxidant Parameters and Abomasal Histopathology in Lambs Experimentally Infected with <i>Haemonchus contortus</i>
Dominika Mravčáková,
Małgorzata Sobczak-Filipiak,
Zora Váradyová,
Katarína Kucková,
Klaudia Čobanová,
Peter Maršík,
Jan Tauchen,
Jaroslav Vadlejch,
Marcin Mickiewicz,
Jaroslaw Kaba,
Marián Várady
Affiliations
Dominika Mravčáková
Institute of Animal Physiology, Centre of Biosciences, Slovak Academy of Sciences, 040 01 Košice, Slovakia
Małgorzata Sobczak-Filipiak
Department of Pathology and Veterinary Diagnostics, Institute of Veterinary Medicine, Warsaw University of Life Sciences, 02-776 Warsaw, Poland
Zora Váradyová
Institute of Animal Physiology, Centre of Biosciences, Slovak Academy of Sciences, 040 01 Košice, Slovakia
Katarína Kucková
Institute of Animal Physiology, Centre of Biosciences, Slovak Academy of Sciences, 040 01 Košice, Slovakia
Klaudia Čobanová
Institute of Animal Physiology, Centre of Biosciences, Slovak Academy of Sciences, 040 01 Košice, Slovakia
Peter Maršík
Institute of Experimental Botany, Czech Academy of Sciences, Prague, 165 02 Lysolaje, Czech Republic
Jan Tauchen
Department of Food Science, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences, 165 00 Prague-Suchdol, Czech Republic
Jaroslav Vadlejch
Department of Zoology and Fisheries, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences, 165 00 Prague-Suchdol, Czech Republic
Marcin Mickiewicz
Division of Veterinary Epidemiology and Economics, Institute of Veterinary Medicine, Warsaw University of Life Sciences, 02-776 Warsaw, Poland
Jaroslaw Kaba
Division of Veterinary Epidemiology and Economics, Institute of Veterinary Medicine, Warsaw University of Life Sciences, 02-776 Warsaw, Poland
Marián Várady
Institute of Parasitology, Slovak Academy of Sciences, 040 01 Košice, Slovakia
This study evaluated the effect of Artemisia absinthium and Malva sylvestris on antioxidant response and histopathological changes in the abomasa of the Haemonchus contortus infected lambs. Twenty-four lambs were divided into four groups: unsupplemented lambs (UNS), lambs supplemented with A. absinthium (ART), lambs supplemented with M. sylvestris (MAL), and lambs supplemented with both plants (ARTMAL). Lambs were infected orally with approximately 5000 third-stage (L3) larvae of H. contortus. The experiment was conducted for 75 d (days), all animals were then slaughtered, and the abomasal tissues were examined for antioxidant parameters and histopathology. The concentration of malondialdehyde in the abomasal mucosa was lower in ARTMAL (p p p p p A. absinthium and M. sylvestris on antioxidant parameters and local immune responses of abomasal mucosa of lambs infected with a GIN parasite.
