Nature Communications (Apr 2021)

Creating enzymes and self-sufficient cells for biosynthesis of the non-natural cofactor nicotinamide cytosine dinucleotide

  • Xueying Wang,
  • Yanbin Feng,
  • Xiaojia Guo,
  • Qian Wang,
  • Siyang Ning,
  • Qing Li,
  • Junting Wang,
  • Lei Wang,
  • Zongbao K. Zhao

DOI
https://doi.org/10.1038/s41467-021-22357-z
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 9

Abstract

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Nicotinamide cytosine dinucleotide is an NAD mimic that can be used to mediate redox reactions. Here the authors design an NCD synthetase for the intracellular production of NCD.